He resigns after nearly dying from being shot because he thinks being Chief isn't his place.
He and Meredith adopt an orphan named Zola from Africa in Season 7.
The two went their separate ways after breaking up, which culminated in them seeing other people.
Jackson started a relationship with the new intern, Stephanie, after hooking up in a car during Bailey's wedding.
April went on to date a paramedic named Matthew Taylor.